Cancer Breakthrough? iNKT Cell Therapy Shows Promise, Stock SKYROCKETS!
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iNKT Cell Therapy: A Potential Game-Changer in Cancer Treatment?
Shares of MiNK Therapeutics Inc. (INKT) are soaring after promising results from their investigational cell therapy, AgenT-797. The therapy, an allogeneic off-the-shelf invariant Natural Killer T (iNKT) cell therapy, is showing potential in treating solid tumors that have become resistant to standard treatments.
A recent publication in the journal Oncogene highlights a remarkable case from a Phase I study. A patient with metastatic, treatment-refractory testicular cancer achieved a complete and durable remission after treatment with AgenT-797. Remarkably, the patient remains disease-free over two years after the treatment.
What is Testicular Cancer?
Testicular cancer, while relatively rare (affecting approximately 1 in 250 males), can be aggressive. This case offers hope for patients who have exhausted other treatment options.
How Does AgenT-797 Work?
AgenT-797 is designed to harness the power of the immune system to fight cancer. iNKT cells act at the interplay between innate and adaptive immune responses. This therapy represents a new approach to treating solid tumors.
Expert Commentary
Dr. Benjamin Garmezy, Assistant Director of Genitourinary Research for Sarah Cannon Research Institute at SCRI Oncology Partners, commented, "This case exemplifies the powerful potential of iNKT cells in treating even the most challenging cancers. We observed a remarkable response in a patient who had exhausted standard and experimental treatments, offering compelling evidence to further pursue clinical studies of iNKT cell therapies in solid tumors".
Another case report published in Oncogene described a patient with metastatic gastric cancer who achieved a 42% tumor reduction and more than nine months of progression-free survival following a single infusion of agenT-797 in combination with Opdivo. These findings warrant further clinical trials.
- AgenT-797 shows promise in treatment-refractory cancers.
- iNKT cell therapy offers a new approach to solid tumor treatment.
- MiNK Therapeutics stock (INKT) has seen a significant surge following the announcement.